Abstract: Taking the Yuqi area in the northern Tarim Basin as an example, with fundamental geology, physical geography, geochemistry and logging data, the paper analyzed petroleum accumulation condition and reservoir model in the study area. Reservoirs can be divided into east, west and central blocks in the Yuqi area, showing significant difference between east block and west block in reservoir formation. Associated with the history data of this petroleum reservoir, some controlling factors of petroleum accumulation were proposed and the favorable exploration area of Yuqi areas was forecasted. The results can provide evidences for further petroleum exploration.