Abstract: According to the basic concepts of sequence stratigraphy and the controlling factors of compressional basins, the continental sequences in the Western Sichuan Depression were studied, based on field outcrops, well cores and logging and seismic data. The episodic compressions of surrounding mountains controlled the sequence stratigraphy and sedimentary infill pattern in the western Sichuan foreland basins. Stress accumulated slowly for a long time, and released instantly. Lake-level (basal level) and accommodation space changed in response to periodic compression and relaxation, resulting in LST (Lowstand System Tract) and T-HST (Transgressive-Highstand System Tract). Coarse-grained sedimentary bodies such as braided river and delta are dominant in LST, while T-HST in the upper part of the sequence is composed of fine-grained semi-deep lacustrine sediments. Vertically, delta facies sand bodies are interbedded with lacustrine mudstones, favorable for hydrocarbon generation, accumulation, preservation and trap formation. Lithologic reservoirs and lithologic-tectonic reservoirs formed by coarse grains at the bottom of the sequence are important exploration targets. Meanwhile, lithologic reservoirs in the upper part of the sequence on the basin margin provide additional opportunities.