Abstract: Acidifacation effect is not ideal in the Tahe Oil Field due to the complicated mineral compostion of clastic rock formations. We optimized the standard for well/formation selection and the formula of acid fracturing fluid. The optimized standard was applied in well YK20 in the Tahe Oil Field, and worked well. For some acidification wells, laboratory flow experiments can not be made due to the absence of core samples. In view of this, we established and solved a numerical simulation model. The calculation results were consistent with the laboratory experiment results. As a result, we can guide acidification design without laboratory flow experiments.