Abstract: The results of pressure sensitivity experiments for 24 horizontal and vertical core samples of low-permeability Carboniferous carbonate reservoir in the depth of T oilfield show that,the relationship of effective pressure and porosity,as following: 1)the pore press-lose ratio of Carboniferous carbonate reservoir correlated with their magnitude of porosity.As a whole,the higher porosity,the lower pore press-lose ratio,vice versa;2)the permeabiltiy press-lose ratio of Carboniferous carbonate reservoir associated with their poro-permeability condition.The well poro-permeability condition,the lesser damage factor,and vice versa.