Abstract: There are mainly three sets of source rocks distributed in the Santanghu Basin:the Middle and Lower Jurassic Shuixugou Group,the Middle and Upper Triassic Xiaoquangou Group and the Permian Shangjijicao Group.At present,oil/gas flow or oil/gas showing is discovered in the grit rock of the Middle Jurassic Xishanyao Formation and the volcanic rock of the Lower Permian Kalagang Formation.In this paper,the main source rocks of the Santanghu Basin and the geochemical characteristics of Permian crude oil are introduced.Based on the total composition of crude oil and source rocks and the compositional characteristics of molecular geochemistry,the oil-source rock correlation is conducted and the main source rocks of Permi an crude oil is analysed.